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M-Audio Oxygen (MKIV) Series - Setup In Ableton Live 9 Lite (1678)

oxygen49 mainThe M-Audio Oxygen 25 (MKIV), Oxygine 49 (MKIV), and Oxygen 61 (MKIV) are professional pad and keyboard controllers designed for hands-on software control, sequencing, and performance. Included with every Oxygen Series keyboard is a software bundle that includes Ableton Live 9 Lite and SONiVOX Twist Spectral Morphing Synthesizer. This guide walks through setting up the Oxygen (MKIV) Series to take control of this powerful software.



  1. Ableton Live 9 Lite Software Setup
  2. Virtual Instruments and Plugins
  3. Additional Resources
  4. Further Product Support


Ableton Live 9 Lite Software Setup

  1. Open Ableton Live 9 Lite.
  2. Navigate to the Preferences menu by making the following selections - 

    Select Live > Preferences
    or use the key command shortcut - [Command + comma]

    Select Options > Preferences
    or use the key command shortcut - [Control + comma]

  3. Click on the MIDI Sync tab.

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  4. Under Control Surface select Oxygen 3rd Gen. Select Oxygen25/49/61 as the Input

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  5. Under MIDI Ports locate the Input for Oxygen 3rd Gen. Turn on Track and Remote.

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  6. Exit the Preferences menu. 

    The transport controls, knobs, and faders of the Oxygen will now be mapped out to Ableton when the AUTO button on the keyboard is pressed. 


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Virtual Instruments and Plugins

Creating an Instrument Track
  1. Click on Instruments under the Categories column.  

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  2. Select an instrument from the column on the right and drag it onto an empty MIDI track in your main Ableton window.

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    The once empty MIDI track will now be an active instrument track and should read your key presses from the Oxygen Series keyboard. 


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Choosing a Plugin Folder

Most DAWS will not load your VST plugins automatically. In order to access 3rd party VST plugins with Ableton, you will need to choose a plugin folder for the software to scan. For the purposes of this article we will be focusing on the included SONiVOX Twist. The default installation will store Twist in the following locations - 

C:\Program Files (x86)\Cakewalk\VST

Macintosh HD\Library\Audio\Plugins\VST

To set your plugin folder in Ableton -

  1. Go to the Preferences menu. 
  2. Select the File Folder tab. 

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  3. Under Plugin-In Sources click Browse and select the appropriate plugin folder. 

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    After making your selection, the Use VST Custom Plug-In Folder button should now be ON. If it is not, click it. 
  4. Exit the Preferences menu. 


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Adding SONiVOX Twist as an Instrument Track

 Now that the plugin folder is set, SONiVOX Twist can be inserted as an instrument track. 

  1. Click on Plug-Ins under the Categories column.

    m-audio oxygen ableton 8
  2. SONiVOX Twist should now be available to select from the column to the right. Just like with Ableton's built in instruments, you can drag Twist to an empty MIDI track. 

    m-audio oxygen ableton 9

    The once empty MIDI track will now be a Twist instrument track and should read your key presses from the Oxygen Series keyboard.

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Additional Resources

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Further Product Support

Whether you are a customer or dealer, if you already own an M-Audio product, or if you just have pre-sales questions, the M-Audio technical support team is available to help!

Visit the link below to connect with any of the following support options: online community support, phone support, email support.

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