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M-Audio Oxygen (MKIV) Series - Frequently Asked Questions

oxygen49 mainThe M-Audio Oxygen 25 (MKIV), Oxygen 49 (MKIV), and Oxygen 61 (MKIV) are professional pad and keyboard controllers designed for hands-on software control, sequencing, and performance. This article walks through a number of Frequently Asked Questions about the M-Audio Oxygen Series controllers.


Frequently Asked Questions



What software does the Oxygen Series come with?

All keyboards in the Oxygen (MKIV) series include download codes for Ableton Live Lite 9 and SONiVOX Twist - Spectral Morphing Synthesizer.


I do not have the authorization codes for my software.  What do I do?

If your authorization code is lost or misplaced, contact M-Audio Technical Support by visiting for further assistance.


What operating systems are supported? Do I need to install any drivers?

The Oxygen (MKIV) series is class compliant, which means you don’t have to download or install any drivers. Being class compliant also means that the Oxygen (MKIV) series will run on all current and future operating systems for PC and Mac.


Will the transport buttons, rotary knobs, and faders control my DAW automatically?

The Oxygen (MKIV) series controllers have DirectLink compatibility. Rather than assigning parameters one by one, DirectLink automatically maps the Oxygen’s controls to many of the most frequently used digital audio workstations. When used with a supported DAW, you can control the transport, mixing controls (faders and panning) and virtual instrument or signal processing plug-in parameters. Current DirectLink support includes Reason, Cubase, Ableton, Pro Tools, Garageband, and Logic.

To enable DirectLink with your Oxygen, you may need to install some additional software. Visit to download the necessary DirectLink driver personalities for your specific DAW.


What are the default MIDI notes for the pads. Can I change the notes sent by the pads?

The default notes assigned to the pads are as follows:

The pads on the Oxygen (MKIV) series are capable of transmitting Note ON/OFF and velocity messages. You can shift all 8 pads simultaneously by a single note or octave.

To shift all eight pads by a single note

  • Hold SHIFT and SELECT and press either the "-" or "+OCTAVE button

To shift all eight pads by an octave

  • Hold SHIFT and press either the "-" or "+OCTAVE button


How do I reset the pads?

Hold SHIFT and both OCTAVE buttons. The pads will light up and then dim to show that they have been reset. 


Can I control my virtual instruments while the Oxygen is already controlling my DAW?

Each keyboard in the Oxygen (MKIV) series has an AUTO button that allows you to switch between controlling your DAW (in the ON position) or your virtual instruments (in the OFF position). 


Can I use the Oxygen (MKIV) series controller with my iPad??

Yes! Any Oxygen (MKIV) series keyboard will be fully powered by your iOS device’s bus power. To use an Oxygen (MKIV) series keyboard with an iPad, connect it using the iPad Camera Connection kit (sold separately).


How do I perform a factory reset?

Hold the "-" and "+" OCTAVE buttons while powering the keyboard on, and it will restore the controller to the factory default settings.

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Further Product Support

Whether you are a customer or dealer, if you already own an M-Audio product, or if you just have pre-sales questions, the M-Audio technical support team is available to help!

Visit the link below to connect with any of the following support options: online community support, phone support, email support.

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